Career Awards at the Scientific Interface

Grant Recipients


2011-2002 Recipients


Ahmed S. Abdelfattah, PhD
Brown University
Probing and manipulating the neural circuitry of opiate addiction using novel optogenetic tools

Zibo Chen, PhD
California Institute of Technology
Molecular programming using de novo designed proteins

Yogesh Goyal, PhD 
University of Pennsylvania
Biochemical trajectories guiding rare cell plasticity and therapy resistance in single cancer cells

Elizabeth R. Jerison, PhD 
Stanford University
Migration and population dynamics in the zebrafish adaptive immune system

Stephanie E. Lindsey, PhD
Stanford University
Quantitation of early great vessel growth and remodeling

Brittany S. Morgan, PhD
Cracking the molecular recognition code: capturing dynamic substructures with small molecules

Cristina Rodriguez, PhD 
University of California - Berkeley
Decoding spinal cord neural circuits through advanced optical imaging methods

Julea Vlassakis, PhD
University of California-Berkeley
Precision oncology via single-cell proteomics

*award will be granted to faculty institution of award recipient


Steven Mark Banik, PhD 
Stanford University
Reprogramming proteins for targeted degradation and intracellular trafficking

Jennifer Ann Noelani Brophy, PhD
Stanford University 
Engineering organ development using synthetic genetic regulation 

Fei Chen, PhD 
Massachusetts Institute of Technology 
Genomic tools for understanding spatial and dynamic organization of biological tissues

Víctor García-López, PhD
Rice University
Molecular machines target, disrupt cell membranes, and kill cancer cells and resistant bacteria

Livnat Jerby, PhD 
Massachusetts Institute of Technology
Deciphering immune evasion mechanisms in cancer with single-cell technologies

Christina K. Kim, PhD 
Stanford University
Simultaneous molecular activity recording and transcriptomics of brainwide neural ensembles

Joseph William Larkin, PhD
University of California-San Diego 
Patterning microbial populations through collective dynamics

Jeffrey E. Markowitz, PhD
Harvard Medical School
Resolving the neural mechanisms of reinforcement learning through new behavioral and optical technologies

Sergey D. Stavisky, PhD 
Stanford University
Brain-computer interfaces to actualize the movements and speech of people with paralysis 

Jeffrey Robert Tithof, PhD
University of Rochester
Experimentally-validated simulations of cerebrospinal fluid flow through the brain’s perivascular network

Mark Wagner, PhD
Stanford University
Computations, recurrent dynamics, and learning in the cortex-cerebellum circuit underlying skilled behavior


Gozde Durmus, DPhil, PhD
Stanford University
Levitating rare biological materials to decode the fundamentals

Kirsten L. Frieda, PhD
California Institute of Technology
Recording cell histories in situ using MEMOIR

Walter Gabriel Gonzalez, PhD
California Institute of Technology
Dynamic control of brain activity and behavioral robustness

Brandon Helfield, PhD
University of Toronto
Biophysics and cell biology of ultrasound-assisted membrane permeabilization for targeted gene delivery

Daniel R. Hochbaum, PhD
Harvard Medical School
Parsing learning-dependent circuit remodeling from spatiotemporally resolved cell states

Chiamaka Denise Okafor, PhD
Emory University
Targeting steroid receptors by uncovering evolutionary mechanisms of activation

Nicolas Christian Pegard, PhD
University of California-Berkeley
Computational optical interfaces for neurosciences and systems biology

Calin Plesa, PhD
University of California-Los Angeles
Ubiquitous biosensing through engineered histidine kinases

Silvia Rouskin, PhD
Massachusetts Institute of Technology
Understanding RNA structure heterogeneity and its role in gene expression and disease

Geoffrey Schiebinger, PhD
Massachusetts Institute of Technology
Analyzing developmental processes with optimal transport

Shahrzad Yazdi, PhD
Massachusetts Institute of Technology
Bridging the origin and function of flows in developmental biology


Scott E. Boyken, PhD
University of Washington
Programmable protein interaction specificity to engineer and interrogate cellular signaling

Gregg A. Duncan, PhD
Johns Hopkins University
Microscale airway surface liquid interactions and their role in obstructive lung diseases

Felipe Garcia Quiroz, PhD
Rockefeller University
Repetitive elements of life: from genomes to proteins and material systems

Kelley Harris, PhD
Stanford University
Decoding the evolutionary history of DNA replication fidelity from whole genome sequences

Felix JH Hol, PhD
Stanford University
Eco-evolutionary dynamics of mosquito-borne viruses

Ashok Litwin-Kumar, PhD
Columbia University
Modeling distributed olfactory learning in rodents and insects

Po-Ru Loh, PhD
Harvard School of Public Health
Toward an early-warning system for leukemia: Characterizing mosaic copy number abnormalities

Tatiana V. Mishanina, PhD
University of Wisconsin-Madison
Visual-kinetic studies of pausing by bacterial RNA polymerase using time-resolved cryo-EM

Octavio Mondragon-Palomino, PhD
California Institute of Technology
In situ dissection of bacteria-bacteria interactions on the mucosa of the mammalian gut

Priya Moorjani, PhD
Columbia University
Learning about the rate and chronology of human evolution

Amy Elizabeth Shyer, PhD
University of California-Berkeley
Investigating mechano-chemical mechanisms of mesenchymal morphogenesis in skin and bone

Amy M. Weeks, PhD
University of California-San Francisco
Untangling the protease web: Chemical and enzymatic probes for dissection of proteolytic signaling in immune cells


Ahmet F. Coskun, Ph.D.
California Institute of Technology
Computational single molecule imaging and barcoding: Exploring cellular identity at the single cell transcript level

Alexander G. Huth, Ph.D.
University of California-Berkeley
Comprehensive functional mapping of human cortex using generative models

Ashley Laughney Bakhoum, Ph.D.
Sloan-Kettering Institute
Uncovering transcriptional vulnerabilities in latent metastasis

Michael J. Mitchell, Ph.D.
Massachusetts Institute of Technology
High-throughput in vivo nucleic acid delivery screening via molecular barcoding of nanoparticles for bone marrow-related diseases

Arthur Prindle, Ph.D.
University of California-San Diego
Electrical signaling and multicellular organization

Adrianne Marie Rosales, Ph.D.
University of Colorado-Boulder
Dynamic viscoelastic hydrogels to study mechanisms of fibrosis

David M. Schneider, Ph.D.
Duke University
Neural circuits for making predictions and learning from mistakes

Amy Wesolowski, Ph.D.
Princeton University
Impact of human travel on infectious disease dynamics

Jing Yan, Ph.D.
Princeton University
Resolving and analyzing living bacterial biofilms at the single cell level

Weijian Yang, Ph.D.
Columbia University
Holographic mapping and manipulation of neuronal microcircuits


Lacramioara Bintu, Ph.D.
California Institute of Technology
Dynamics of epigenetic regulation at the single-cell level

Alistair Nicol Boettiger, Ph.D.
Harvard University
Direct imaging of the nanoscale structural organization of chromatin as shaped by developmental signals

Julijana Gjorgjieva, Ph.D.
Brandeis University
Deriving network behavior from single neuron biophysics, synaptic plasticity and neuromodulation

Ann M Hermundstad, Ph.D.
University of Pennsylvania
Beyond independence: emergent neural function and the natural world

Markita Patricia Landry, Ph.D.
Massachusetts Institute of Technology
Synthetic antibodies for real-time monitoring of cellular protein imbalances and protein misfolding

Monica M Laronda, Ph.D.
Northwestern University
Engineering an artificial ovary to restore fertility and endocrine function in cancer survivors

Chen Li, Ph.D.
University of California-Berkeley
The terradynamics of biological movement in complex terrain

Francisco Eduardo Robles, Ph.D.
Duke University
Molecular imaging based on the linear and nonlinear refractive index for biomedical applications

Allyson E Sgro, Ph.D.
Princeton University
Greater as a whole: bridging intracellular signaling and population behaviors in collective systems

Jeffrey Neil Stirman, Ph.D.
University of North Carolina-Chapel Hill
Trepan2p Microscopy: panoramic brain imaging with cellular resolution for systems neuroscience

Vivek Venkatachalam, Ph.D.
Harvard University
Lifetime behavior and neurophysiology in C. elegans

Christina May Woo, Ph.D.
Stanford University
Expansion of the druggable proteome: understanding proteome-wide small molecule--protein interactions


Ariana E Anderson, Ph.D.
University of California-Los Angeles
It's all in your head: isolating the placebo effect in the brain to reduce drug development costs

Amit Choudhary, Ph.D.
Harvard University / Broad Institute
Snakes, antioxidants, and diabetes

Matthew C Good, Ph.D.
University of California-Berkeley
Cell size and shape dependence of intracellular assembly and signaling

Prashant Mali, Ph.D.
Harvard Medical School
Engineering normal and diseased liver organogenesis

Nikhil S Malvankar, Ph.D.
University of Massachusetts-Amherst
Direct visualization of charge flow in individual native biomolecules

Elizabeth A Nance, Ph.D.
Johns Hopkins University
Nanoparticle-mediated targeted therapies for pediatric brain disorders

Elizabeth Hesper Rego, Ph.D.
Harvard School of Public Health
Drug use on the single cell level: differential antibiotic susceptibility of mycobacterial cells using fluorescent reporters.

Ramkumar Sabesan, Ph.D.
University of California-Berkeley School of Optometry
Studying visual function on a cellular scale

Kimberly Murley Stroka, Ph.D.
Johns Hopkins University School of Medicine
Engineering blood-brain barrier mechanobiology in tumor metastasis

Michael D. Vahey, Ph.D.
University of California-Berkeley School of Public Health
Uncovering the dynamics of enveloped virus assembly

Heng Xu, Ph.D.
Baylor College of Medicine
Deciphering stochastic transcriptional regulation at the single-event level

Xin Zhang, Ph.D.
Scripps Research Institute
Scrutinizing the cellular and molecular mechanisms that create and maintain the functional proteome using chemical probes


Gregory R. Bowman, Ph.D.
University of California - Berkeley
Decrypting cryptic allosteric sites resulting from protein flexibility

Yaniv Erlich, Ph.D.
Whitehead Institute for Biomedical Research
Dissecting complex phenotypes using web 2.0 social networks

Stephanie I. Fraley, Ph.D.
Johns Hopkins University School of Medicine
Digitizing microRNA: integrated profiling and discovery for rapid, quantitative, and broad-scale detection in infectious disease

Hernan G. Garcia, Ph.D.
Princeton University
Wiring up the synthetic fly

Karen E. Kasza, Ph.D.
Memorial Sloan-Kettering Cancer Center
Mechanical cues coordinating cell behaviors during morphogenesis

Gabriel Kwong, Ph.D.
Massachusetts Institute of Technology
Nanoparticles that amplify biomarkers in vivo for ultrasensitive metastasis monitoring

Megan N. McClean, Ph.D.
Princeton University
Optogenetic and microfluidic tools for generating dynamic inputs to interrogate and control biological networks

Mikhail G. Shapiro, Ph.D.
University of California - Berkeley
Genetically encoded reporters for sensitive non-invasive imaging of biological function

Paul A. Sigala, Ph.D.
Washington University
Mechanistic probes of heme metabolism in malaria parasites

Bo Wang, Ph.D.
University of Illinois-Urbana-Champaign
In vivo imaging and functional genomic analysis of stem cells in human parasitic worm schistosoma


Buz M. Barstow, Ph.D.
Harvard Medical School
Evolving the limits of metabolism and in vivo catalysis

ShiNung Ching, Ph.D.
Harvard Medical School
Towards treatments in disorders of consciousness and new models of general anesthesia

Kwanghun Chung, Ph.D.
Stanford University
Clear, Lipid-exchanged, Anatomically Rigid, Imaging/immunostaining-compatible, Tissue hYdrogel (CLARITY) technology for high-throughput and high-content whole tissue analysis

Robert Gregg, Ph.D.
Northwestern University
From machine to biomimetic control in robot-assisted walking

Maureen E. Hillenmeyer, Ph.D.
Stanford University
In vivo synthetic evolution of bioactive natural products

Allon Moshe Klein, Ph.D.
Harvard Medical School
Defining patterns and mechanisms of stem cell fate choice

Sergey A. Kryazhimskiy, Ph.D.
Harvard University
Predicting evolution in microbial populations

Heather J. Kulik, Ph.D.
Stanford University
Deciphering the role of the protein scaffold in enzyme catalysis with fast and accurate computation

Lulu Qian, Ph.D.
California Institute of Technology
Exploring and re-realizing the principles of information processing in biology using artificial nucleic-acid systems

Jesse G. Zalatan, Ph.D.
University of California - San Francisco
Entropic contributions to efficiency in biochemical networks